Pharmaceutical Intermediates

Ethyl 4,4,4-trifluorocrotonate CAS:25597-16-4 98%min

Chemical Name:Ethyl 4,4,4-trifluorocrotonate
CAS.NO:25597-16-4
Synonyms:Ethyl 4,4,4-trifluorocrotonate;4,4,4-Trifluorocrotonic acid ethyl ester
Molecular Formula:C6H7F3O2
Molecular Weight:168.11400
Physical and Chemical Properties:
Density:1.125;
Boiling point:114-115oC;
Flash point:78oF;
Index of Refraction:1.3601;
Description:
Medical&Pesticide intermediate;
The upstream raw material is Ethyl 4,4,4-trifluoroacetoacetate and Ethyl 3-hydroxy-4,4,4-trifluorobutyrate;
Ethyl 4,4,4-trifluoroacetoacetate is reduced by NaBH4 to give Ethyl 3-hydroxy-4,4,4-trifluorobutyrate, and then reacted with P2O5 to obtain the product.
 
Specification:
Appearance Colorless liquid
Assay ≥97.0%
 

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